What compounds target CYP3A7?

BiohacksAI has identified 205 compounds that interact with CYP3A7 (cytochrome P450 family 3 subfamily A member 7). Top compounds include: Glyburide, Ritonavir, Losartan, Buspirone, Disulfiram. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is CYP3A7 (cytochrome P450 family)?

CYP3A7 is cytochrome P450 family 3 subfamily A member 7. It is a molecular target for 205 compounds documented in PubMed bioassay data. UniProt ID: P24462. NCBI Gene ID: 1551.

CYP3A7

MOLECULAR TARGET

cytochrome P450 family 3 subfamily A member 7

UniProt: P24462 NCBI Gene: 1551205 compounds

CYP3A7 (cytochrome P450 family 3 subfamily A member 7) is targeted by 205 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting CYP3A7

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	Glyburide	1.95	6
2	Ritonavir	1.95	6
3	Losartan	1.61	4
4	Buspirone	1.61	4
5	Disulfiram	1.61	4
6	Estrone	1.61	4
7	Ezetimibe	1.61	4
8	Flumethasone	1.61	4
9	Furazolidone	1.61	4
10	Maprotiline	1.61	4
11	Nitrofurazone	1.61	4
12	Ondansetron	1.61	4
13	Piperonyl Butoxide	1.61	4
14	Testosterone Propionate	1.61	4
15	vinblastine sulfate	1.61	4
16	Voriconazole	1.39	3
17	Amlodipine	1.10	2
18	Apigenin 5,7,4'-trihydroxy-flavone,	1.10	2
19	Pueraria	1.10	2
20	Dehydroepiandrosterone	1.10	2
21	Fluoxetine	1.10	2
22	Thyroxine	1.10	2
23	Methylene Blue	1.10	2
24	Mianserin	1.10	2
25	Kaempferols	1.10	2
26	propyl gallate	1.10	2
27	Simvastatin	1.10	2
28	vinpocetine	1.10	2
29	Vitamin K 2	1.10	2
30	17-alpha-Hydroxyprogesterone	1.10	2
31	17 alpha-Hydroxyprogesterone Caproate Hydroxyprogesterone derivative that acts as	1.10	2
32	Abacavir	1.10	2
33	Aminopyrine	1.10	2
34	Amitriptyline Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent	1.10	2
35	amlexanox	1.10	2
36	Amoxapine	1.10	2
37	Anastrozole	1.10	2
38	Androstenedione	1.10	2
39	Aprepitant	1.10	2
40	Aripiprazole	1.10	2
41	Artemether	1.10	2
42	Atrasentan	1.10	2
43	Axitinib	1.10	2
44	Beclomethasone	1.10	2
45	Betamethasone Valerate	1.10	2
46	Bromocriptine	1.10	2
47	Bufotenin	1.10	2
48	candesartan cilexetil [Supplementary Concept]	1.10	2
49	Canrenone	1.10	2
50	Carbaryl	1.10	2

Showing top 50 of 205 compounds. Use the BiohacksAI search to explore all CYP3A7 modulators.

About CYP3A7 as a Drug Target

CYP3A7 (cytochrome P450 family 3 subfamily A member 7) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 205 compounds with documented CYP3A7 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

CYP3A7 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.