euchromatic histone lysine methyltransferase 2
EHMT2 (euchromatic histone lysine methyltransferase 2) is targeted by 18 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | ebselen | 4.74 | 113 |
| 2 | sinefungin | 3.74 | 41 |
| 3 | naphthoquinone | 3.58 | 35 |
| 4 | raltitrexed | 3.58 | 35 |
| 5 | ditiocarb sodium | 3.53 | 33 |
| 6 | chaetocin | 2.94 | 18 |
| 7 | thiram | 2.48 | 11 |
| 8 | Disulfiram | 1.95 | 6 |
| 9 | chetomin | 1.95 | 6 |
| 10 | s adenosylhomocysteine | 1.79 | 5 |
| 11 | benzene selenoic acid | 1.79 | 5 |
| 12 | Cyproheptadine | 1.39 | 3 |
| 13 | Gliotoxin | 1.10 | 2 |
| 14 | Glutathione | 0.69 | 1 |
| 15 | Anthraquinones Compounds based on ANTHRACENES which contain two KETONES in | 0.69 | 1 |
| 16 | Dimethyl Sulfoxide | 0.69 | 1 |
| 17 | ninhydrin | 0.69 | 1 |
| 18 | bdb chembl2172426 | 0.69 | 1 |
EHMT2 (euchromatic histone lysine methyltransferase 2) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 18 compounds with documented EHMT2 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
EHMT2 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.