HTR1F
MOLECULAR TARGET5-hydroxytryptamine receptor 1F
HTR1F (5-hydroxytryptamine receptor 1F) is targeted by 21 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting HTR1F
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | Sumatriptan | 2.56 | 12 |
| 2 | Metergoline | 2.08 | 7 |
| 3 | Methysergide | 1.95 | 6 |
| 4 | Dihydroergotamine | 1.61 | 4 |
| 5 | Ergotamine | 1.61 | 4 |
| 6 | Yohimbine | 1.61 | 4 |
| 7 | Mianserin | 1.10 | 2 |
| 8 | Quetiapine Fumarate | 1.10 | 2 |
| 9 | brl 15572 | 1.10 | 2 |
| 10 | Mescaline Hallucinogenic alkaloid isolated from | 1.10 | 2 |
| 11 | Methylergonovine | 1.10 | 2 |
| 12 | Pergolide | 1.10 | 2 |
| 13 | Fluoxetine | 0.69 | 1 |
| 14 | Amitriptyline Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent | 0.69 | 1 |
| 15 | Bufotenin | 0.69 | 1 |
| 16 | Cyproheptadine | 0.69 | 1 |
| 17 | Metoclopramide | 0.69 | 1 |
| 18 | Nortriptyline | 0.69 | 1 |
| 19 | Pindolol | 0.69 | 1 |
| 20 | Quipazine | 0.69 | 1 |
| 21 | Tamsulosin | 0.69 | 1 |
About HTR1F as a Drug Target
HTR1F (5-hydroxytryptamine receptor 1F) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 21 compounds with documented HTR1F interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
HTR1F inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.