BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
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Quetiapine

A dibenzothiazepine and ANTIPSYCHOTIC AGENT that targets the SEROTONIN 5-HT2 RECEPTOR; HISTAMINE H1 RECEPTOR, adrenergic alpha1 and alpha2 receptors, as well as the DOPAMINE D1 RECEPTOR and DOPAMINE D2 RECEPTOR. It is used in the treatment of SCHIZOPHRENIA; BIPOLAR DISORDER and DEPRESSIVE DISORDER.

994+ PubMed studies analyzed · 391 RCTs · Evidence Score: 73.6

Research Domains

Quetiapine has been studied across 14 research domains including 🌤️ Mood & Depression, 😴 Sleep, 🧘 Stress & Anxiety, 🧠 Neuroprotection, 🧠 Focus & Attention. The primary research focus is 🌤️ Mood & Depression with 23% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Quetiapine, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Mianserin
37 shared targets
Pergolide
29 shared targets
Amitriptyline
40 shared targets
Trazodone
25 shared targets
Lisuride
26 shared targets
Dihydroergotamine
28 shared targets
Cyproheptadine
36 shared targets
Yohimbine
26 shared targets
Promethazine
31 shared targets
Loxapine
27 shared targets
Loading evidence profile...

This evidence profile for Quetiapine is generated deterministically from 994 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.