Dengue virus modulates apoptosis
REACTOME PATHWAYThe Dengue virus modulates apoptosis pathway (Reactome ID: R-HSA-9920951) involves 8 genes and is affected by 32 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Dengue virus modulates apoptosis
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | torin 1 | — | 10 |
| 2 | Ku 0063794 [Supplementary Concept] | — | 7 |
| 3 | Sirolimus | — | 300 |
| 4 | Everolimus | — | 297 |
| 5 | pictilisib | — | 25 |
| 6 | Wortmannin | — | 300 |
| 7 | ly294002 | — | 11 |
| 8 | Rotenone | — | 300 |
| 9 | Thapsigargin | — | 300 |
| 10 | alpelisib | — | 227 |
| 11 | amn082 | — | 29 |
| 12 | Calcimycin | — | 216 |
| 13 | Idarubicin | — | 299 |
| 14 | Idazoxan | — | 300 |
| 15 | Niclosamide | — | 299 |
| 16 | triolimus [Supplementary Concept] | — | 33 |
| 17 | tyrphostin 9 | — | 2 |
| 18 | egcg | — | 300 |
| 19 | Ursolic Acid | — | 300 |
| 20 | Camptothecin | — | 300 |
| 21 | Dequalinium | — | 136 |
| 22 | Disulfiram | — | 297 |
| 23 | Emetine | — | 298 |
| 24 | Epinephrine | — | 299 |
| 25 | Isoproterenol Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on | — | 299 |
| 26 | Maprotiline | — | 299 |
| 27 | Perphenazine | — | 297 |
| 28 | Sorafenib | — | 300 |
| 29 | Crizotinib | — | 298 |
| 30 | Dasatinib | — | 299 |
| 31 | sp600125 | — | 117 |
| 32 | chicoric acid | — | 117 |
About the Dengue virus modulates apoptosis Pathway
The Dengue virus modulates apoptosis pathway is catalogued in Reactome (ID: R-HSA-9920951) and involves 8 genes. In the BiohacksAI corpus, 32 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include MAPKAP1, MLST8, MTOR, NFKBIA, PIK3C3.