What genes are in the Reversible hydration of carbon dioxide pathway?

The Reversible hydration of carbon dioxide pathway involves 12 genes. Key genes include: CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6.

Reversible hydration of carbon dioxide

Q: What compounds affect the Reversible hydration of carbon dioxide pathway?

71 compounds in the BiohacksAI corpus have documented interactions with genes in the Reversible hydration of carbon dioxide pathway (Reactome ID: R-HSA-1475029). These compounds target 12 genes within this pathway.

REACTOME PATHWAY

Reactome: R-HSA-147502912 genes71 compounds

The Reversible hydration of carbon dioxide pathway (Reactome ID: R-HSA-1475029) involves 12 genes and is affected by 71 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.

Genes in this Pathway

CA1 CA12 CA13 CA14 CA2 CA3 CA4 CA5A CA5B CA6 CA7 CA9

Compounds Affecting Reversible hydration of carbon dioxide

#	Compound	Targets Hit	Studies
1	Zonisamide	—	297
2	Indapamide	—	299
3	Bortezomib	—	300
4	Resveratrol	—	298
5	Sulfanilamide	—	300
6	Famotidine	—	296
7	Lacosamide	—	297
8	Celecoxib	—	295
9	benzolamide	—	188
10	Histidine	—	158
11	Chlorthalidone	—	299
12	Furosemide	—	298
13	Quercetin	—	300
14	Bumetanide	—	299
15	stx64	—	2
16	caffeic acid	—	300
17	Catechin	—	51
18	Spermidine	—	241
19	Metolazone	—	166
20	Sulpiride	—	299
21	Histamine	—	300
22	Vanillic Acid	—	300
23	4-Hydroxybenzoate-3-Monooxygenase	—	300
24	Mafenide	—	169
25	chrysin	—	300
26	Phenol	—	297
27	Spermine	—	300
28	Tyrosine	—	43
29	Tyrosine	—	300
30	Hydrogen Sulfide	—	299
31	Hydrogen Sulfide	—	300
32	Sulfides Chemical groups containing	—	300
33	Acetaminophen Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as	—	1,000
34	Acetaminophen Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as	—	293
35	Luteolin 5,7,3',4'-tetrahydroxy-flavone,	—	150
36	Levodopa	—	297
37	Hydrogen Cyanide Hydrogen cyanide (HCN);	—	298
38	d609	—	49
39	Catechin	—	300
40	isorhamnetin-3-O-beta-D-glucopyranosyl-(1-3)-alpha-L-rhamnopyranosyl-(1-6)-beta-D-galactopyranoside [Supplementary Concept] from	—	300
41	Salicylic Acid	—	298
42	Apigenin 5,7,4'-trihydroxy-flavone,	—	300
43	ninhydrin	—	300
44	Sildenafil Citrate	—	300
45	thiamine	—	299
46	Probenecid	—	298
47	tyrosol	—	300
48	Kaempferols	—	300
49	Tryptophan	—	300
50	Pueraria	—	300

About the Reversible hydration of carbon dioxide Pathway

The Reversible hydration of carbon dioxide pathway is catalogued in Reactome (ID: R-HSA-1475029) and involves 12 genes. In the BiohacksAI corpus, 71 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include CA1, CA12, CA13, CA14, CA2.