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Compounds Similar to Duloxetine

10 compounds with shared biological targets · BiohacksAI corpus current

The compounds below share molecular targets and biological mechanisms with Duloxetine, including interactions with CYP2D6, CYP3A4, CYP1A2. Similarity is calculated using target-weighted Jaccard scoring across the BiohacksAI BindingDB corpus. Higher shared target counts indicate stronger mechanistic overlap.

Similar Compounds — Ranked by Target Overlap
15
shared
299
studies
27%
overlap
2
prochlorperazine
15
shared
27%
overlap
3
fananserin
13
shared
25%
overlap
4
thioridazine
16
shared
25%
overlap
5
clemastine
14
shared
24%
overlap
6
ritanserin
14
shared
24%
overlap
7
clomipramine
13
shared
23%
overlap
16
shared
96
studies
23%
overlap
9
brexpiprazole
14
shared
23%
overlap
10
ziprasidone
11
shared
22%
overlap
Shared Biological Targets

Click a target to see all compounds with interactions at that molecular target.

Similarity between compounds is computed using IDF-weighted Jaccard scoring across shared molecular targets in the BiohacksAI BindingDB corpus. Compounds with higher overlap scores share more targets, weighted by how specific those targets are across the entire corpus.

Explore related resources: Duloxetine full profile · Browse all compounds · Biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.