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Compounds Similar to Rapamycin

10 compounds with shared biological targets · BiohacksAI corpus v20260307-01

The compounds below share molecular targets and biological mechanisms with Rapamycin, including interactions with FKBP1A, FKBP1B, CHAIN. Similarity is calculated using target-weighted Jaccard scoring across the BiohacksAI BindingDB corpus. Higher shared target counts indicate stronger mechanistic overlap.

Similar Compounds — Ranked by Target Overlap
1
sirolimus
9
shared
22%
overlap
10
shared
297
studies
21%
overlap
15
shared
11
studies
19%
overlap
11
shared
300
studies
15%
overlap
8
shared
227
studies
15%
overlap
6
tacrolimus
6
shared
14%
overlap
7
torin
9
shared
10
studies
14%
overlap
8
pf
6
shared
12%
overlap
9
ly
7
shared
11%
overlap
10
buparlisib
6
shared
11%
overlap
Shared Biological Targets

Click a target to see all compounds with interactions at that molecular target.

Similarity between compounds is computed using IDF-weighted Jaccard scoring across shared molecular targets in the BiohacksAI BindingDB corpus. Compounds with higher overlap scores share more targets, weighted by how specific those targets are across the entire corpus.

Explore related resources: Rapamycin full profile · Browse all compounds · Biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.