A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
Phentolamine has been studied across 17 research domains including ❤️ Cardiovascular, 🧠 Focus & Attention, ♀♂ Sexual Health, 🔥 Metabolic, 🌤️ Mood & Depression. The primary research focus is ❤️ Cardiovascular with 20% of studies addressing this area.
The following compounds share molecular targets with Phentolamine, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.
This evidence profile for Phentolamine is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.
Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.