What compounds target IFNG?

BiohacksAI has identified 86 compounds that interact with IFNG (interferon gamma). Top compounds include: Dacarbazine, Homoharringtonine Semisynthetic derivative of harringtonine that acts as, 2-Methoxyestradiol, Hexachlorophene, Anisomycin. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is IFNG (interferon gamma)?

IFNG is interferon gamma. It is a molecular target for 86 compounds documented in PubMed bioassay data. UniProt ID: P01579. NCBI Gene ID: 3458.

IFNG

MOLECULAR TARGET

interferon gamma

UniProt: P01579 NCBI Gene: 345886 compounds

IFNG (interferon gamma) is targeted by 86 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting IFNG

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	Dacarbazine	1.95	6
2	Homoharringtonine Semisynthetic derivative of harringtonine that acts as	1.95	6
3	2-Methoxyestradiol	1.79	5
4	Hexachlorophene	1.79	5
5	Anisomycin	1.61	4
6	Benzethonium Bactericidal cationic quaternary ammonium surfactant used as	1.61	4
7	Bortezomib	1.61	4
8	Camptothecin	1.61	4
9	cycloheximide	1.61	4
10	Dasatinib	1.61	4
11	Desoxycorticosterone Acetate	1.61	4
12	tyrphostin 9	1.61	4
13	Quercetin	1.39	3
14	Azathioprine	1.39	3
15	Crizotinib	1.39	3
16	Econazole	1.39	3
17	Mycophenolic Acid Compound derived from Penicillium stoloniferum and related species. It blocks de novo biosynthesis of purine nucleotides by inhibition of	1.39	3
18	Nocodazole Nocodazole is	1.39	3
19	Sorafenib	1.39	3
20	Ursolic Acid	1.10	2
21	Afatinib	1.10	2
22	alsterpaullone	1.10	2
23	Chlorhexidine	1.10	2
24	Cholecalciferol Derivative of 7-dehydroxycholesterol formed by ULTRAVIOLET RAYS breaking of	1.10	2
25	Clofarabine	1.10	2
26	Clotrimazole	1.10	2
27	Dactinomycin	1.10	2
28	darapladib [Supplementary Concept]	1.10	2
29	Daunorubicin	1.10	2
30	Digitoxigenin 3 beta,14-Dihydroxy-5 beta-card-20(22)enolide.	1.10	2
31	Digoxigenin 3 beta,12 beta,14-Trihydroxy-5 beta-card-20(22)-enolide.	1.10	2
32	Epirubicin	1.10	2
33	Estrone	1.10	2
34	Ethinyl Estradiol	1.10	2
35	Fulvestrant	1.10	2
36	Idarubicin	1.10	2
37	Irinotecan	1.10	2
38	Levonorgestrel	1.10	2
39	Miconazole	1.10	2
40	Nandrolone C18 steroid with androgenic and anabolic properties. It is generally prepared from alkyl ethers of ESTRADIOL to resemble TESTOSTERONE but less	1.10	2
41	Niclosamide	1.10	2
42	Norgestrel	1.10	2
43	Novobiocin	1.10	2
44	Perphenazine	1.10	2
45	Podophyllotoxin	1.10	2
46	scriptaid	1.10	2
47	Teniposide	1.10	2
48	Topotecan	1.10	2
49	Tripterygium	1.10	2
50	Vemurafenib	1.10	2

Showing top 50 of 86 compounds. Use the BiohacksAI search to explore all IFNG modulators.

About IFNG as a Drug Target

IFNG (interferon gamma) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 86 compounds with documented IFNG interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

IFNG inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.