What compounds target IFNB1?

BiohacksAI has identified 47 compounds that interact with IFNB1 (interferon beta 1). Top compounds include: Camptothecin, Ouabain, withaferin, celastrol, Disulfiram. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is IFNB1 (interferon beta 1)?

IFNB1 is interferon beta 1. It is a molecular target for 47 compounds documented in PubMed bioassay data. UniProt ID: P01574. NCBI Gene ID: 3456.

IFNB1

MOLECULAR TARGET

interferon beta 1

UniProt: P01574 NCBI Gene: 345647 compounds

IFNB1 (interferon beta 1) is targeted by 47 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting IFNB1

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	Camptothecin	2.48	11
2	Ouabain	2.40	10
3	withaferin	2.30	9
4	celastrol	2.08	7
5	Disulfiram	2.08	7
6	Idarubicin	2.08	7
7	Bortezomib	1.95	6
8	cycloheximide	1.95	6
9	Emetine	1.95	6
10	Proscillaridin	1.95	6
11	Crizotinib	1.79	5
12	Dactinomycin	1.79	5
13	Daunorubicin	1.79	5
14	Epirubicin	1.79	5
15	Homoharringtonine Semisynthetic derivative of harringtonine that acts as	1.79	5
16	trichostatic acid [Supplementary Concept] related to trichostatin	1.79	5
17	Tripterygium	1.79	5
18	Azacitidine	1.61	4
19	Azacitidine	1.61	4
20	Calcimycin	1.61	4
21	3-(1-(3-hydroxy-4-methoxyphenyl)methylidene)-6-methylchroman-4-one [Supplementary Concept]	1.61	4
22	kenpaullone	1.61	4
23	cbd	1.39	3
24	cannabidiol	1.39	3
25	Deslanoside Deacetyllanatoside C.	1.39	3
26	Digitoxin	1.39	3
27	Digoxin	1.39	3
28	Feprazone	1.39	3
29	Leflunomide	1.39	3
30	triolimus [Supplementary Concept]	1.39	3
31	Thapsigargin	1.39	3
32	Genistein	1.10	2
33	Sertraline	1.10	2
34	Nitrendipine	1.10	2
35	Phenylbutazone	1.10	2
36	Luteolin 5,7,3',4'-tetrahydroxy-flavone,	0.69	1
37	Methylene Blue	0.69	1
38	Warfarin	0.69	1
39	Afatinib	0.69	1
40	C75-coenzyme	0.69	1
41	casin	0.69	1
42	Fluspirilene	0.69	1
43	Isopentenyladenosine N(6)-[delta(3)-isopentenyl]adenosine. Isopentenyl derivative of adenosine which is	0.69	1
44	Sorafenib	0.69	1
45	sp600125	0.69	1
46	Trabectedin	0.69	1
47	tyrphostin ag 1478	0.69	1

About IFNB1 as a Drug Target

IFNB1 (interferon beta 1) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 47 compounds with documented IFNB1 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

IFNB1 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.