What compounds target MUSCARINIC?

BiohacksAI has identified 32 compounds that interact with MUSCARINIC (Muscarinic acetylcholine receptor M5 (human)). Top compounds include: Hyoscyamine, Quetiapine Fumarate, Amoxapine, Nortriptyline, Mianserin. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is MUSCARINIC (Muscarinic acetylcholine receptor)?

MUSCARINIC is Muscarinic acetylcholine receptor M5 (human). It is a molecular target for 32 compounds documented in PubMed bioassay data. UniProt ID: P08912.

MUSCARINIC

MOLECULAR TARGET

Muscarinic acetylcholine receptor M5 (human)

UniProt: P0891232 compounds

MUSCARINIC (Muscarinic acetylcholine receptor M5 (human)) is targeted by 32 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting MUSCARINIC

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	Hyoscyamine	3.47	31
2	Quetiapine Fumarate	2.48	11
3	Amoxapine	2.48	11
4	Nortriptyline	2.48	11
5	Mianserin	2.40	10
6	Amitriptyline Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent	2.40	10
7	Astemizole Antihistamine drug now withdrawn from	2.40	10
8	Cyclizine	2.40	10
9	Cyproheptadine	2.40	10
10	Dimenhydrinate	2.40	10
11	Maprotiline	2.40	10
12	Promethazine	2.40	10
13	Sertraline	2.20	8
14	Cinnarizine	2.20	8
15	Econazole	2.20	8
16	Flunarizine Flunarizine is	2.20	8
17	Miconazole	2.20	8
18	Clotrimazole	1.95	6
19	pentamidine	1.95	6
20	Arecoline	1.79	5
21	N-Methylscopolamine	1.79	5
22	Scopolamine	1.79	5
23	Oxymetazoline	1.61	4
24	Ethylestrenol	1.10	2
25	Irinotecan	1.10	2
26	Muscarine	1.10	2
27	Pilocarpine	1.10	2
28	Danazol	0.69	1
29	Dimethindene	0.69	1
30	Ipratropium	0.69	1
31	Loxapine	0.69	1
32	Metergoline	0.69	1

About MUSCARINIC as a Drug Target

MUSCARINIC (Muscarinic acetylcholine receptor M5 (human)) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 32 compounds with documented MUSCARINIC interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

MUSCARINIC inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.