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BiohacksAI/Research Domains/Endurance & Cardio
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Compounds Studied for Endurance & Cardio Pathways

Endurance physiology involves mitochondrial efficiency, oxygen transport, and metabolic flexibility. Published research has documented compounds in relation to VO2max markers, fat oxidation, lactate accumulation, and recovery-associated biological pathways.

MITOCHONDRIA pathway →AMPK pathway →NITRIC OXIDE pathway →
Top 9 Compounds — Ranked by Evidence
Weighted ranking: BiohacksAI discovery score · pathway overlap · PubMed study count
1
Astragalusfeatured
300+
studies
2
Beta-Alaninefeatured
300+
studies
3
Citrullinefeatured
amino acid
4
Coenzyme Q10featured
coenzyme
5
Cordycepsfeatured
279+
studies
6
Creatinefeatured
298+
studies
7
Ironfeatured
296+
studies
8
Rhodiola Roseafeatured
300+
studies
9
Sodium Bicarbonatefeatured
299+
studies
Ranking Methodology
Compounds are ranked using a four-signal weighted model: BiohacksAI discovery score (cross-study convergence across targets), target match (direct overlap with PPARGC1A, PRKAA1, NOS3 and related targets — highest differentiating signal), pathway overlap with goal-relevant pathways, and PubMed study count (log-scaled). Clinical drugs are excluded.
Key Molecular Targets
PPARGC1APRKAA1NOS3EPAS1SLC2A4

Click a target to see all compounds with documented interactions.

Related Research Domains
⚡ Energy & Mitochondria research💪 Strength & Muscle research♾️ Longevity & Anti-Aging research

Rankings based on BiohacksAI discovery score, pathway overlap, and PubMed study count. All data is deterministic and corpus-verified. Not medical advice.

Browse all compounds · Biological pathways · Molecular targets · Health conditions

Data: PubMed/NCBI, BindingDB, Reactome. © Organiq Sweden AB · Patent pending EVE-PAT-2026-001