What genes are in the RUNX3 regulates YAP1-mediated transcription pathway?

The RUNX3 regulates YAP1-mediated transcription pathway involves 2 genes. Key genes include: TEAD4, YAP1.

RUNX3 regulates YAP1-mediated transcription

Q: What compounds affect the RUNX3 regulates YAP1-mediated transcription pathway?

42 compounds in the BiohacksAI corpus have documented interactions with genes in the RUNX3 regulates YAP1-mediated transcription pathway (Reactome ID: R-HSA-8951671). These compounds target 2 genes within this pathway.

REACTOME PATHWAY

Reactome: R-HSA-89516712 genes42 compounds

The RUNX3 regulates YAP1-mediated transcription pathway (Reactome ID: R-HSA-8951671) involves 2 genes and is affected by 42 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.

Genes in this Pathway

TEAD4 YAP1

Compounds Affecting RUNX3 regulates YAP1-mediated transcription

#	Compound	Targets Hit	Studies
1	Colchicine	—	300
2	Resveratrol	—	298
3	Daunorubicin	—	298
4	Rotenone	—	300
5	Pueraria	—	300
6	Azacitidine	—	298
7	Azacitidine	—	300
8	Camptothecin	—	300
9	cycloheximide	—	300
10	Dactinomycin	—	297
11	deguelin [Supplementary Concept]	—	151
12	Harmine Alkaloid isolated from seeds of PEGANUM HARMALA; ZYGOPHYLLACEAE. It is identical to banisterine, or telepathine, from Banisteria caapi and is	—	300
13	Mycophenolic Acid Compound derived from Penicillium stoloniferum and related species. It blocks de novo biosynthesis of purine nucleotides by inhibition of	—	300
14	Ouabain	—	300
15	Podophyllotoxin	—	14
16	Thapsigargin	—	300
17	Berberine	—	300
18	Genistein	—	300
19	2-Methoxyestradiol	—	300
20	Anisomycin	—	247
21	Antimycin	—	300
22	Azauridine	—	300
23	Benzalkonium Compounds	—	299
24	celastrol	—	300
25	Cetylpyridinium Cationic bactericidal surfactant used as	—	300
26	Digoxigenin 3 beta,12 beta,14-Trihydroxy-5 beta-card-20(22)-enolide.	—	300
27	dihydrorotenone	—	13
28	Emetine	—	298
29	Gliotoxin	—	300
30	Homoharringtonine Semisynthetic derivative of harringtonine that acts as	—	300
31	Monensin	—	300
32	Monocrotaline	—	300
33	Nigericin	—	300
34	Nocodazole Nocodazole is	—	215
35	Plicamycin	—	72
36	Strophanthidin 3 beta,5,14-Trihydroxy-19-oxo-5 beta-card-20(22)-enolide.	—	300
37	Tilorone	—	300
38	Tripterygium	—	300
39	Tubercidin	—	300
40	tyrphostin 9	—	2
41	Valinomycin	—	300
42	Niflumic Acid	—	300

About the RUNX3 regulates YAP1-mediated transcription Pathway

The RUNX3 regulates YAP1-mediated transcription pathway is catalogued in Reactome (ID: R-HSA-8951671) and involves 2 genes. In the BiohacksAI corpus, 42 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include TEAD4, YAP1.