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Compounds Similar to Psilocybin

10 compounds with shared biological targets · BiohacksAI corpus current

The compounds below share molecular targets and biological mechanisms with Psilocybin, including interactions with HTR2A, HTR2B, 5-HYDROXYTRYPTAMINE. Similarity is calculated using target-weighted Jaccard scoring across the BiohacksAI BindingDB corpus. Higher shared target counts indicate stronger mechanistic overlap.

Similar Compounds — Ranked by Target Overlap
1
sb
3
shared
56%
overlap
2
rs
3
shared
56%
overlap
3
nn
3
shared
47%
overlap
4
lorcaserin
3
shared
47%
overlap
5
sb
3
shared
46%
overlap
3
shared
300
studies
42%
overlap
7
pimavanserin
2
shared
37%
overlap
8
pizotyline
3
shared
36%
overlap
9
mesulergine
3
shared
35%
overlap
10
glaucine
3
shared
32%
overlap
Shared Biological Targets

Click a target to see all compounds with interactions at that molecular target.

Similarity between compounds is computed using IDF-weighted Jaccard scoring across shared molecular targets in the BiohacksAI BindingDB corpus. Compounds with higher overlap scores share more targets, weighted by how specific those targets are across the entire corpus.

Explore related resources: Psilocybin full profile · Browse all compounds · Biological targets · Biological pathways

Data from BindingDB and PubMed. For research purposes only. Not medical advice.