What genes are in the Respiratory Syncytial Virus Infection Pathway pathway?

The Respiratory Syncytial Virus Infection Pathway pathway involves 25 genes. Key genes include: CCNC, CDK19, CDK8, CREBBP, CSNK2A1, CSNK2A2, CSNK2B, CX3CR1, EGFR, EIF2AK2.

Respiratory Syncytial Virus Infection Pathway

Q: What compounds affect the Respiratory Syncytial Virus Infection Pathway pathway?

121 compounds in the BiohacksAI corpus have documented interactions with genes in the Respiratory Syncytial Virus Infection Pathway pathway (Reactome ID: R-HSA-9820952). These compounds target 25 genes within this pathway.

REACTOME PATHWAY

Reactome: R-HSA-982095225 genes121 compounds

The Respiratory Syncytial Virus Infection Pathway pathway (Reactome ID: R-HSA-9820952) involves 25 genes and is affected by 121 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.

Genes in this Pathway

CCNC CDK19 CDK8 CREBBP CSNK2A1 CSNK2A2 CSNK2B CX3CR1 EGFR EIF2AK2 EP300 FURIN HSP90AA1 HSP90AB1 HSPA8 IFNB1 IGF1R KPNB1 PPP1CA PPP1CC RBX1 TLR2 TLR3 TYK2 XPO1

Compounds Affecting Respiratory Syncytial Virus Infection Pathway

#	Compound	Targets Hit	Studies
1	Quercetin	—	300
2	myricetin-3-O-galactopyranoside [Supplementary Concept]	—	300
3	ly294002	—	11
4	Crizotinib	—	298
5	Luteolin 5,7,3',4'-tetrahydroxy-flavone,	—	150
6	Sorafenib	—	300
7	sp600125	—	117
8	celastrol	—	300
9	Idarubicin	—	299
10	Calcimycin	—	216
11	triolimus [Supplementary Concept]	—	33
12	Masoprocol	—	300
13	Tetracycline	—	300
14	ag490	—	14
15	Hexachlorophene	—	300
16	Apigenin 5,7,4'-trihydroxy-flavone,	—	300
17	Emodin Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as	—	300
18	fisetin	—	78
19	Kaempferols	—	300
20	chrysin	—	300
21	Vanillic Acid	—	300
22	alsterpaullone	—	12
23	Axitinib	—	298
24	Disulfiram	—	297
25	cycloheximide	—	300
26	kenpaullone	—	8
27	Afatinib	—	297
28	Fluspirilene	—	74
29	tyrphostin ag 1478	—	4
30	19-((1'S,4'R)-4'-hydroxy-1'-methoxy-2'-oxopentyl)geldanamycin [Supplementary Concept]	—	300
31	monorden	—	8
32	gedunin	—	54
33	Novobiocin	—	300
34	caffeic acid	—	300
35	Zearalenone (S-(E))-3,4,5,6,8,10-Hexahydro-14,16-dihydroxy-3-methyl-1H-2-benzoxacyclotetradec in-1,7(8H)-dione.	—	300
36	Adenylyl Imidodiphosphate 5'-Adenylic acid, monoanhydride with imidodiphosphoric acid.	—	300
37	Clotrimazole	—	296
38	piceatannol	—	300
39	Nitroprusside	—	299
40	Chlorhexidine	—	299
41	pictilisib	—	25
42	plumbagin [Supplementary Concept]	—	300
43	Camptothecin	—	300
44	Ouabain	—	300
45	withaferin	—	300
46	Bortezomib	—	300
47	Emetine	—	298
48	Proscillaridin	—	219
49	Dactinomycin	—	297
50	Daunorubicin	—	298

About the Respiratory Syncytial Virus Infection Pathway Pathway

The Respiratory Syncytial Virus Infection Pathway pathway is catalogued in Reactome (ID: R-HSA-9820952) and involves 25 genes. In the BiohacksAI corpus, 121 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include CCNC, CDK19, CDK8, CREBBP, CSNK2A1.