What compounds affect the Viral Infection Pathways pathway?

577 compounds in the BiohacksAI corpus have documented interactions with genes in the Viral Infection Pathways pathway (Reactome ID: R-HSA-9824446). These compounds target 203 genes within this pathway.

What genes are in the Viral Infection Pathways pathway?

The Viral Infection Pathways pathway involves 203 genes. Key genes include: ADRM1, AKT3, APOBEC3G, ATP1A1, ATP1A2, ATP1A3, ATP1A4, ATP1B1, ATP1B2, ATP1B3.

Viral Infection Pathways

REACTOME PATHWAY

Reactome: R-HSA-9824446203 genes577 compounds

The Viral Infection Pathways pathway (Reactome ID: R-HSA-9824446) involves 203 genes and is affected by 577 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.

Genes in this Pathway

ADRM1 AKT3 APOBEC3G ATP1A1 ATP1A2 ATP1A3 ATP1A4 ATP1B1 ATP1B2 ATP1B3 AXL BCL2L1 BRD4 BTK CAMK2B CAMK2D CASP1 CBX1 CCNC CCNT2 CDK19 CDK7 CDK8 CDK9 CGAS CHUK CHURC1-FNTB CREB1 CREBBP CSNK1A1+173 more

Compounds Affecting Viral Infection Pathways

#	Compound	Targets Hit	Studies
1	Bortezomib	—	300
2	Quercetin	—	300
3	Podophyllotoxin	—	14
4	Crizotinib	—	298
5	Nocodazole Nocodazole is	—	215
6	Sorafenib	—	300
7	Colchicine	—	300
8	Vorinostat	—	299
9	vinblastine sulfate	—	81
10	sp600125	—	117
11	Vincristine	—	299
12	Hexachlorophene	—	300
13	Reserpine	—	297
14	Digitoxin	—	300
15	Disulfiram	—	297
16	Demecolcine	—	246
17	Digoxin	—	299
18	Ouabain	—	300
19	Noscapine	—	300
20	Luteolin 5,7,3',4'-tetrahydroxy-flavone,	—	150
21	myricetin-3-O-galactopyranoside [Supplementary Concept]	—	300
22	Maytansine	—	300
23	Dasatinib	—	299
24	alsterpaullone	—	12
25	kenpaullone	—	8
26	Apigenin 5,7,4'-trihydroxy-flavone,	—	300
27	Axitinib	—	298
28	Daunorubicin	—	298
29	ly294002	—	11
30	egcg	—	300
31	chrysin	—	300
32	cycloheximide	—	300
33	Camptothecin	—	300
34	Kaempferols	—	300
35	trichostatic acid [Supplementary Concept] related to trichostatin	—	300
36	Idarubicin	—	299
37	pictilisib	—	25
38	Emodin Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as	—	300
39	Ethidium	—	300
40	tyrphostin ag 1478	—	4
41	Calcimycin	—	216
42	Genistein	—	300
43	Methylene Blue	—	200
44	Nisoldipine	—	297
45	Masoprocol	—	300
46	Lovastatin	—	300
47	piceatannol	—	300
48	torin 1	—	10
49	Afatinib	—	297
50	Astemizole Antihistamine drug now withdrawn from	—	280

About the Viral Infection Pathways Pathway

The Viral Infection Pathways pathway is catalogued in Reactome (ID: R-HSA-9824446) and involves 203 genes. In the BiohacksAI corpus, 577 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include ADRM1, AKT3, APOBEC3G, ATP1A1, ATP1A2.