What compounds target SODIUM-DEPENDENT?

BiohacksAI has identified 58 compounds that interact with SODIUM-DEPENDENT (Sodium-dependent noradrenaline transporter (human)). Top compounds include: Venlafaxine Hydrochloride, Sertraline, Amitriptyline Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent, Venlafaxine Hydrochloride, Metergoline. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

SODIUM-DEPENDENT

Q: What is SODIUM-DEPENDENT (Sodium-dependent noradrenaline transporter)?

SODIUM-DEPENDENT is Sodium-dependent noradrenaline transporter (human). It is a molecular target for 58 compounds documented in PubMed bioassay data. UniProt ID: P23975.

MOLECULAR TARGET

Sodium-dependent noradrenaline transporter (human)

UniProt: P2397558 compounds

SODIUM-DEPENDENT (Sodium-dependent noradrenaline transporter (human)) is targeted by 58 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting SODIUM-DEPENDENT

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	Venlafaxine Hydrochloride	2.77	15
2	Sertraline	2.40	10
3	Amitriptyline Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent	2.40	10
4	Venlafaxine Hydrochloride	2.20	8
5	Metergoline	2.08	7
6	Aripiprazole	1.95	6
7	Astemizole Antihistamine drug now withdrawn from	1.95	6
8	Carvedilol	1.95	6
9	Celecoxib	1.95	6
10	Cinnarizine	1.95	6
11	Clotrimazole	1.95	6
12	Econazole	1.95	6
13	Ethinyl Estradiol	1.95	6
14	Flunarizine Flunarizine is	1.95	6
15	Miconazole	1.95	6
16	Nortriptyline	1.95	6
17	Danazol	1.79	5
18	Promethazine	1.79	5
19	Mianserin	1.61	4
20	2-Acetylaminofluorene	1.61	4
21	2-Hydroxypropyl-beta-cyclodextrin Derivative of beta-cyclodextrin that is used as	1.61	4
22	Amoxapine	1.61	4
23	Dimenhydrinate	1.61	4
24	Domperidone	1.61	4
25	Ethylestrenol	1.61	4
26	Labetalol	1.61	4
27	Leflunomide	1.61	4
28	Maprotiline	1.61	4
29	Mestranol	1.61	4
30	pentamidine	1.61	4
31	Cyproheptadine	1.39	3
32	Fluvoxamine	1.39	3
33	Ibogaine	1.39	3
34	Lovastatin	1.39	3
35	Modafinil	1.10	2
36	Resveratrol	1.10	2
37	17-alpha-Hydroxyprogesterone	1.10	2
38	Cyclizine	1.10	2
39	Dextromethorphan Methyl analog of DEXTRORPHAN that shows high affinity binding to several regions of	1.10	2
40	Disulfiram	1.10	2
41	Estrone	1.10	2
42	Fenofibrate	1.10	2
43	Hexachlorophene	1.10	2
44	Levobunolol	1.10	2
45	Nocodazole Nocodazole is	1.10	2
46	Norethindrone	1.10	2
47	Pemoline	1.10	2
48	Propranolol	1.10	2
49	protriptyline	1.10	2
50	Riluzole	1.10	2

Showing top 50 of 58 compounds. Use the BiohacksAI search to explore all SODIUM-DEPENDENT modulators.

About SODIUM-DEPENDENT as a Drug Target

SODIUM-DEPENDENT (Sodium-dependent noradrenaline transporter (human)) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 58 compounds with documented SODIUM-DEPENDENT interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

SODIUM-DEPENDENT inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.