BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
BiohacksAI is an evolving scientific literature platform. New compounds and evidence are indexed continuously.
B
○
BiohacksAI/Compounds/Spironolactone
✓ FULLY PROFILED

Spironolactone

298+ PubMed studies analyzed · BiohacksAI corpus v20260307-01

Spironolactone 2D molecular structure
PubMed Studies
298+
Targets
10
Pathways
10
Molecular Targets
ARGLUCOCORTICOIDCYP19A1ESR1ESRRANFE2L2CYP1A2CYP2C19CYP2D6ESR2

Molecular targets identified in BiohacksAI corpus. Click to explore all compounds affecting each target.

Biological Pathways
TESTOSTERONE_HORMONESINFLAMMATIONCORTISOL_STRESSNITRIC_OXIDEOXIDATIVE_STRESSIMMUNE_FUNCTIONGLUCOSE_METABOLISMAPOPTOSISINSULIN_SIGNALINGCOLLAGEN_ECM

Biological pathways associated with Spironolactone based on target analysis.

Biological Mechanisms
NF-κBNF-κBHPAHPA AxisNONitric OxideNRF2Nrf2NLRP3NLRP3 InflammasomeIRSInsulin Signaling

Biological mechanisms activated or modulated by Spironolactone based on pathway and target analysis.

Health Goals
Hormone Balance →Strength →Inflammation →Longevity →Stress →

Health goals where Spironolactone ranks among evidence-based compounds in the BiohacksAI corpus.

Related Conditions
PCOS →Acne →Chronic Inflammation →Arthritis →Chronic Stress →

Health conditions associated with the biological pathways influenced by Spironolactone.

External References
PubChem CID 5833 →298 PubMed studies →
Similar Compounds

Explore compounds with similar target profiles and pathway overlap.

Find similar compounds to Spironolactone →
Data Source
Corpusv20260307-01
PubMed studies298
PubChem CID5833
SourcePubMed / NCBI · ChEMBL · Reactome · PubChem

All data is computationally derived from published research. Molecular structure images from PubChem (public domain). Not medical advice. Independent validation required.

This compound profile for Spironolactone is generated from 298 PubMed-indexed studies. Key molecular targets include AR, GLUCOCORTICOID, CYP19A1. Associated biological pathways: TESTOSTERONE_HORMONES, INFLAMMATION, CORTISOL_STRESS. BiohacksAI does not provide medical advice. Consult a healthcare professional before starting any supplement regimen.