What compounds affect the RHOBTB3 ATPase cycle pathway?

49 compounds in the BiohacksAI corpus have documented interactions with genes in the RHOBTB3 ATPase cycle pathway (Reactome ID: R-HSA-9706019). These compounds target 2 genes within this pathway.

What genes are in the RHOBTB3 ATPase cycle pathway?

The RHOBTB3 ATPase cycle pathway involves 2 genes. Key genes include: HTR7, RAB9A.

RHOBTB3 ATPase cycle

REACTOME PATHWAY

Reactome: R-HSA-97060192 genes49 compounds

The RHOBTB3 ATPase cycle pathway (Reactome ID: R-HSA-9706019) involves 2 genes and is affected by 49 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.

Genes in this Pathway

HTR7 RAB9A

Compounds Affecting RHOBTB3 ATPase cycle

#	Compound	Targets Hit	Studies
1	Mianserin	—	299
2	Aripiprazole	—	298
3	Metergoline	—	144
4	Cyproheptadine	—	299
5	Lysergic Acid Diethylamide Semisynthetic derivative of ergot (Claviceps purpurea). It has complex effects on serotonergic systems including antagonism at some peripheral serotonin receptors, both agonist and antagonist actions at central nervous system serotonin receptors, and possibly effects on serotonin turnover. It is	—	298
6	Methysergide	—	300
7	Sumatriptan	—	298
8	Vortioxetine	—	294
9	Loxapine	—	225
10	Quetiapine Fumarate	—	994
11	Amitriptyline Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent	—	299
12	Amoxapine	—	259
13	Bufotenin	—	93
14	Buspirone	—	299
15	Lisuride	—	299
16	Pergolide	—	299
17	Perphenazine	—	297
18	Amisulpride	—	298
19	Dihydroergotamine	—	299
20	Dihydroergotamine	—	9
21	Mescaline Hallucinogenic alkaloid isolated from	—	300
22	Phenylephrine	—	299
23	Astemizole Antihistamine drug now withdrawn from	—	280
24	Bromocriptine	—	299
25	Butaclamol	—	300
26	Carvedilol	—	296
27	Ergotamine	—	299
28	Harmaline	—	300
29	Harmine Alkaloid isolated from seeds of PEGANUM HARMALA; ZYGOPHYLLACEAE. It is identical to banisterine, or telepathine, from Banisteria caapi and is	—	300
30	Hydroxyzine	—	298
31	Nortriptyline	—	295
32	pirenperone	—	22
33	Pramipexole	—	297
34	Quipazine	—	300
35	Ritonavir	—	298
36	Sorafenib	—	300
37	Tamsulosin	—	298
38	Yohimbine	—	299
39	Pueraria	—	300
40	Genistein	—	300
41	pterostilbene	—	299
42	amlexanox	—	96
43	kenpaullone	—	8
44	Leflunomide	—	297
45	Niclosamide	—	299
46	pd98059	—	7
47	Phenelzine	—	297
48	Riluzole	—	298
49	tyrphostin ag 1295	—	1

About the RHOBTB3 ATPase cycle Pathway

The RHOBTB3 ATPase cycle pathway is catalogued in Reactome (ID: R-HSA-9706019) and involves 2 genes. In the BiohacksAI corpus, 49 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include HTR7, RAB9A.