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DRD3 Modulators

COMPOUND CLUSTER

527 compoundscohesion 0.170cluster #2

The DRD3 Modulators cluster contains 527 compounds grouped by shared molecular target interactions, computed via Louvain community detection on the BiohacksAI target interaction graph.

Compounds in this Cluster

Fluoxetine1,001 studies Amlodipine1,000 studies Escitalopram S-enantiomer of CITALOPRAM. Belongs to996 studies Venlafaxine Hydrochloride1,000 studies Quetiapine Fumarate994 studies Duloxetine Hydrochloride993 studies Tamsulosin298 studies Sumatriptan298 studies Bisoprolol297 studies Timolol298 studies Pindolol299 studies Metoclopramide297 studies Cetirizine296 studies Atenolol297 studies Nefopam Non-narcotic analgesic chemically similar to ORPHENADRINE. Its mechanism of action is unclear. It is used for299 studies Xamoterol275 studies Pramipexole297 studies Labetalol295 studies Reboxetine298 studies Celiprolol300 studies Vortioxetine294 studies Cabergoline299 studies Nadolol297 studies Nortriptyline295 studies Amisulpride298 studies Dexmedetomidine299 studies Trazodone297 studies Aripiprazole298 studies Psilocybin300 studies Penbutolol246 studies Oxprenolol300 studies Tolterodine Tartrate73 studies Dolutegravir298 studies Levobunolol211 studies Encainide300 studies Acebutolol298 studies Ranolazine297 studies Metaproterenol298 studies Benzydamine298 studies Phenylephrine299 studies Fenoterol300 studies Oxymetazoline298 studies Bromocriptine299 studies Viloxazine296 studies Venlafaxine Hydrochloride122 studies Dexpramipexole50 studies Guanfacine294 studies Hydroxyzine298 studies Nebivolol297 studies Loxapine225 studies Ergonovine299 studies Dimethindene119 studies Pergolide299 studies Raclopride300 studies Clonidine299 studies Dihydroergotamine299 studies Amitriptyline Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent299 studies Carteolol299 studies Caspofungin299 studies Clindamycin298 studies Norepinephrine Precursor of epinephrine that is secreted by298 studies Mianserin299 studies Ivabradine293 studies Methylergonovine193 studies Yohimbine299 studies Metergoline144 studies Carvedilol296 studies Alprenolol300 studies Piribedil300 studies Dihydroergotoxine208 studies Chlorpheniramine298 studies Phentolamine300 studies Methoxamine300 studies Oxaprozin181 studies Bufotenin93 studies Prenalterol300 studies Thiethylperazine165 studies Leukotriene B4300 studies Indoramin250 studies Oxyfedrine144 studies Dihydroergocryptine257 studies Bupranolol291 studies Phenylpropanolamine300 studies Lisuride299 studies Cyproheptadine299 studies Penicillin G298 studies protriptyline296 studies Aprindine300 studies Cyclizine251 studies Cyclic AMP300 studies Nylidrin90 studies Antazoline229 studies Platelet Activating Factor300 studies Dihydroergocornine65 studies Propafenone14 studies Rilmenidine Oxazole derivative that acts as300 studies Quipazine300 studies Ritodrine87 studies Cyclic AMP300 studies Lysergic Acid Diethylamide Semisynthetic derivative of ergot (Claviceps purpurea). It has complex effects on serotonergic systems including antagonism at some peripheral serotonin receptors, both agonist and antagonist actions at central nervous system serotonin receptors, and possibly effects on serotonin turnover. It is298 studies Methysergide300 studies Tolazoline300 studies Piperoxan167 studies Ergotamine299 studies Flavin Mononucleotide299 studies Butaclamol300 studies Naphazoline298 studies Guanabenz298 studies Mescaline Hallucinogenic alkaloid isolated from300 studies Meclizine121 studies Rauwolfia200 studies Ibogaine300 studies Practolol300 studies Sulfaguanidine255 studies SCH 23390 [Supplementary Concept]126 studies Ivermectin298 studies Clenbuterol300 studies Tetrahydropapaveroline139 studies Benzethonium Bactericidal cationic quaternary ammonium surfactant used as96 studies Triethylenephosphoramide28 studies amn08229 studies pirenperone22 studies nafadotride14 studies ethopropazine17 studies bdb chembl8197 ics 205 930 tropisetron9 studies Dihydroergotamine9 studies Tiapride Hydrochloride2 studies bdb asxgaofckghgmf5 studies brl 155722 studies bdb endo 8 1h indol 3 ylmethyl 3 4 chlorophenyl 8 azabicyclo 3 2 1 octan 3 ol 3 4 ch3 studies bdb chembl5519273 studies bdb chembl5628333 studies bdb chembl5649303 studies bdb chembl50830252 studies bdb chembl50806542 studies bdb chembl50757262 studies bdb chembl50724492 studies bdb chembl50750142 studies bdb chembl50831862 studies bdb chembl50865642 studies bdb chembl50771142 studies bdb chembl50824652 studies bdb chembl47894722 studies bdb chembl47466952 studies bdb chembl50776452 studies bdb chembl46374092 studies bdb 3 9 10 dihydro anthracen 9 yloxy 8 methyl 8 aza bicyclo 3 2 1 octane chembl320112 studies bdb 3 4 chloro phenyl phenyl methoxy 8 methyl 8 aza bicyclo 3 2 1 octane chembl540032 studies bdb 2 1h pyrrolo 2 3 b pyridin 3 yl methyl 5 4 chlorophenyl 2 5 diazabicyclo 2 2 1 h2 studies bdb 2 3 bis 4 fluoro phenyl methoxy 8 aza bicyclo 3 2 1 oct 8 ylmethyl 1h indole che2 studies bdb 4 6 4 chlorophenyl 2 6 diazabicyclo 2 2 1 heptan 2 yl 1 4 fluorophenyl butan 1 o2 studies bdb 3 3 chloro phenyl phenyl methoxy 8 3 phenyl propyl 8 aza bicyclo 3 2 1 octane ch2 studies bdb 3 bis 4 fluoro phenyl methoxy 8 2 bis 4 fluoro phenyl methoxy ethyl 8 aza bicycl2 studies bdb endo 8 1h indol 3 ylmethyl 3 4 fluorophenyl 8 azabicyclo 3 2 1 octan 3 ol chembl2 studies bdb endo 8 1h indol 3 ylmethyl 3 2 naphthyl 8 azabicyclo 3 2 1 octan 3 ol chembl49412 studies bdb endo 8 naphtho 1 2 b fur 3 ylmethyl 3 4 chlorophenyl 8 azabicyclo 3 2 1 octan 3 2 studies bdb endo 8 naphtho 2 1 b fur 1 ylmethyl 3 4 chlorophenyl 8 azabicyclo 3 2 1 octan 3 2 studies bdb endo 8 5 methoxybenzofur 3 ylmethyl 3 4 chlorophenyl 8 azabicyclo 3 2 1 octan 3 2 studies bdb endo 8 5 fluorobenzofur 3 ylmethyl 3 3 4 dichlorophenyl 8 azabicyclo 3 2 1 octan2 studies bdb endo 8 5 fluorobenzofur 3 ylmethyl 3 4 chlorophenyl 8 azabicyclo 3 2 1 octan 3 o2 studies bdb endo 8 benzofur 3 ylmethyl 3 4 bromophenyl 8 azabicyclo 3 2 1 octan 3 ol chembl42 studies bdb endo 8 5 methoxy 1h indol 3 ylmethyl 3 4 chlorophenyl 8 azabicyclo 3 2 1 octan 32 studies bdb endo 8 1h indol 3 ylmethyl 3 4 methylthio phenyl 8 azabicyclo 3 2 1 octan 3 ol c2 studies bdb endo 8 1h indol 3 ylmethyl 3 2 3 dichlorophenyl 8 azabicyclo 3 2 1 octan 3 ol ch2 studies bdb endo 8 benzofur 3 ylmethyl 3 4 fluorophenyl 8 azabicyclo 3 2 1 octan 3 ol chembl2 studies bdb endo 8 benzothien 3 ylmethyl 3 3 4 dichlorophenyl 8 azabicyclo 3 2 1 octan 3 ol 2 studies bdb endo 8 benzofur 3 ylmethyl 3 2 3 dichlorophenyl 8 azabicyclo 3 2 1 octan 3 ol ch2 studies bdb endo 8 5 methoxy 1h indol 3 ylmethyl 3 4 methylthiophenyl 8 azabicyclo 3 2 1 oct2 studies bdb chembl19467442 studies bdb endo 8 1h indazol 3 ylmethyl 3 4 chlorophenyl 8 azabicyclo 3 2 1 octan 3 ol chem2 studies bdb endo 8 benzofur 3 ylmethyl 3 3 4 dichlorophenyl 8 azabicyclo 3 2 1 octan 3 ol ch2 studies bdb endo 8 benzothien 3 ylmethyl 3 2 3 dichlorophenyl 8 azabicyclo 3 2 1 octan 3 ol 2 studies bdb n 4 4 fluoro butyrophenone 4 azahexacyclo 5 4 1 0 2 6 0 3 10 0 5 9 0 8 11 dodeca2 studies bdb endo 8 benzothien 3 ylmethyl 3 4 chlorophenyl 8 azabicyclo 3 2 1 octan 3 ol chem2 studies bdb endo 8 benzofur 3 ylmethyl 3 4 chlorophenyl 8 azabicyclo 3 2 1 octan 3 ol chembl2 studies bdb endo 8 1h indol 3 ylmethyl 3 3 4 dichlorophenyl 8 azabicyclo 3 2 1 octan 3 ol ch2 studies bdb 4 3 4 chlorophenyl 3 9 diazabicyclo 4 2 1 nonan 9 yl 1 4 fluorophenyl butan 1 on2 studies bdb chembl19461222 studies bdb chembl19467452 studies bdb chembl19461232 studies bdb chembl22058132 studies bdb n 2 3 fluorophenyl ethyl n methyl 8 aminopentacyclo 5 4 0 02 6 03 10 05 9 undeca2 studies bdb hoiihacbcfljet2 studies bdb chembl12371492 studies chlorprothixene hydrochloride1 studies olanzapine0 studies brexpiprazole0 studies prochlorperazine0 studies fananserin0 studies clemastine0 studies clomipramine0 studies risperidone0 studies nantenine0 studies clozapine0 studies ziprasidone0 studies ritanserin0 studies l 7458700 studies paliperidone0 studies silodosin0 studies cariprazine0 studies droperidol0 studies ebastine0 studies promazine0 studies thioridazine0 studies fluphenazine0 studies salmeterol0 studies doxepin0 studies ergocornine0 studies spiperone0 studies bp 8970 studies sertindole0 studies bay 2930 studies spiroxatrine0 studies penfluridol0 studies ipsapirone0 studies niguldipine0 studies lysergide0 studies ropinirole0 studies fauc 1130 studies azaperone0 studies rotigotine0 studies eticlopride0 studies iolopride0 studies dihydroergocristine mesylate0 studies zotepine0 studies ketotifen fumarate0 studies latrepirdine0 studies terfenadine0 studies terconazole0 studies mespiperone0 studies pd 1680770 studies benperidol0 studies methapyrilene0 studies asenapine0 studies canadine0 studies quinpirole0 studies talipexole0 studies sultopride0 studies orphenadrine0 studies desloratadine0 studies mirtazapine0 studies ketotifen0 studies isoclozapine0 studies sumanirole0 studies 8 oh dpat0 studies enclomiphene0 studies haloprogin0 studies preclamol0 studies dexchlorpheniramine0 studies dopamine hydrochloride0 studies mepazine0 studies 5 oh dpat0 studies mazapertine0 studies ketanserin0 studies stepholidine0 studies nemonapride0 studies oxiconazole0 studies raloxifene0 studies tiapride0 studies pyrilamine0 studies diethylstilbestrol0 studies clebopride0 studies doxazosin0 studies clonidine hydrochloride0 studies sb 2587410 studies benzethonium chloride0 studies sulconazole0 studies gentian violet0 studies armodafinil0 studies formoterol0 studies indacaterol0 studies r n propylnorapomorphine0 studies cetylpyridinium bromide0 studies psilocin0 studies dicyclomine0 studies chlorophenylpiperazine0 studies diphenidol0 studies tetrahydropalmatine0 studies citalopram0 studies tamoxifen0 studies amiodarone0 studies serotonin0 studies sb 2587190 studies dopamine0 studies rauwolscine0 studies idalopirdine0 studies chlorprothixene0 studies quinacrine0 studies benzothiazyl disulfide0 studies mesulergine0 studies brimonidine0 studies corynantheine0 studies vilazodone0 studies volinanserin0 studies terazosin0 studies diphenhydramine0 studies dexniguldipine0 studies imipramine0 studies propafenone0 studies dibenzepin0 studies mebufotenin0 studies levopropranolol0 studies pizotyline0 studies mosapride0 studies oxybutynin0 studies loperamide0 studies 5 methoxytryptamine0 studies rs ifenprodil0 studies pptn0 studies mitotane0 studies prazosin0 studies azelastine0 studies a 3498210 studies gr 1279350 studies intepirdine0 studies nn dimethyltryptamine0 studies desvenlafaxine0 studies methylphenidate0 studies nomifensine0 studies nisoxetine0 studies 4 methylthioamphetamine0 studies midomafetamine0 studies indatraline0 studies levomilnacipran0 studies milnacipran0 studies esreboxetine0 studies tenamfetamine0 studies cocaine hydrochloride0 studies difluorobenztropine0 studies glaucine0 studies fluoxetine hydrochloride0 studies ecopipam0 studies nefazodone0 studies sr ifenprodil0 studies paroxetine0 studies vanoxerine0 studies propranolol hydrochloride0 studies bithionol0 studies way 1006350 studies mazindol0 studies ciglitazone0 studies sibutramine0 studies sb 2432130 studies auranofin0 studies amitifadine0 studies rizatriptan0 studies bmy 73780 studies lorcaserin0 studies lurasidone0 studies desipramine0 studies hydroxychloroquine0 studies dextroamphetamine0 studies 4 nonylphenol0 studies nan 1900 studies roxindole0 studies atomoxetine0 studies thimerosal0 studies lofexidine0 studies loperamide hydrochloride0 studies aplysinopsin0 studies butenafine0 studies bupropion0 studies sb 2420840 studies rs 1022210 studies 1 naphthylisothiocyanate0 studies pimozide0 studies mk 2120 studies cirazoline0 studies abt 7240 studies prazosin hydrochloride0 studies yohimbine hydrochloride0 studies dihydrexidine0 studies metitepine0 studies ticlopidine0 studies tirilazad0 studies gepirone0 studies biphenyline0 studies berberine chloride0 studies darifenacin0 studies irdabisant0 studies estradiol benzoate0 studies isoloxapine0 studies bisphenol a0 studies sch 233900 studies perhexiline0 studies cyclazosin0 studies naftopidil0 studies nelfinavir0 studies dexpropranolol0 studies tryptamine0 studies s ifenprodil0 studies pimavanserin0 studies l 3652600 studies phenothiazine0 studies alfuzosin0 studies cinanserin0 studies hinokinin0 studies methysergide maleate0 studies closantel0 studies l 7646460 studies l 7555070 studies levisoprenaline0 studies r skf 383930 studies apraclonidine0 studies gsk7780 studies moxonidine0 studies s reticuline0 studies conessine0 studies bromotopsentin0 studies nortopsentin c0 studies nortopsentin b0 studies nortopsentin a0 studies a 4850 studies cgp 20712a0 studies ciproxifan0 studies tretoquinol0 studies purvalanola0 studies zenidolol0 studies thioperamide0 studies terbinafine0 studies bay 11 70850 studies selegiline0 studies sibenadet0 studies chlorpromazine hydrochloride0 studies bifeprunox0 studies fenoldopam0 studies ru 249690 studies frovatriptan0 studies zolmitriptan0 studies naratriptan0 studies clorotepine0 studies talinolol0 studies borussertib0 studies skepinone l0 studies namodenoson0 studies candesartan0 studies skf 383930 studies oxitriptan0 studies carbetapentane0 studies bufotenine0 studies xylometazoline0 studies ly 2940020 studies isotretinoin0 studies tacrine0 studies bromhexine0 studies rabeprazole0 studies transplatin0 studies tolvaptan0 studies plerixafor0 studies 3 methylcholanthrene0 studies ifenprodil0 studies pitolisant0 studies alosetron0 studies fexofenadine0 studies mizolastine0 studies mli 20 studies tropisetron0 studies pridopidine0 studies bmy 148020 studies hydroxyhaloperidol0 studies mk 72460 studies e doxepin0 studies snap 79410 studies mexiletine0 studies amantadine0 studies amentoflavone0 studies siramesine0 studies ly 2552830 studies benzodefchrysene0 studies mavorixafor0 studies 5 carboxy adenosine0 studies gold sodium thiomalate0 studies ambroxol0 studies tracizoline0 studies danuglipron0 studies indinavir0 studies nabumetone0 studies epinastine0 studies bay 8760 studies gsk0460 studies methoxsalen0 studies pantoprazole0 studies imiquimod0 studies bisacodyl0 studies disopyramide0 studies rimantadine0 studies paclitaxel0 studies gsk6200 studies abamectin0 studies amsacrine0 studies docetaxel0 studies tetramethylkaempferol0 studies cyclopamine0 studies phenylguanidine0 studies camostat0 studies trioxsalen0 studies tadalafil0 studies tolnaftate0 studies phenylpiperazine0 studies mk 02490 studies nn hexamethyleneamiloride0 studies amprenavir0 studies amiloride0 studies wedelolactone0 studies cp 963450 studies zacopride0 studies trimipramine0 studies trovafloxacin0 studies palonosetron0 studies beta naphthoflavone0 studies chloroxylenol0 studies vesamicol0 studies tenatoprazole0 studies norfluoxetine0 studies vismodegib0 studies traxoprodil0 studies hypericin0 studies rel cisapride0 studies scutellarin0 studies rr tramadol0 studies flupentixol0 studies dnl 2010 studies proanthocyanidin a10 studies tryptoline0 studies halopemide0 studies zuclopenthixol0 studies cyclobenzaprine0 studies